VU0463271

Product Specifications

CAS Number

1391737-01-1

Target

Potassium Channel

Applications

Transmembrane Transporters

Molecular Formula

C19H18N4OS2

Additionnal Information

VU0463271 is a selective and potent antagonist of neuronal-specific potassium-chloride cotransporter 2 KCC2, with an IC50 of 61 nM. VU0463271 demonstrates over 100-fold selectivity compared to the closely related Na-K-2Cl cotransporter 1 (NKCC1) .

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