What is the catalog number for Elsubrutinib?

The catalog number for Elsubrutinib is C01770-5mg.

What sizes are available for Elsubrutinib?

Elsubrutinib is available in the following size(s): 5 mg.

Is Elsubrutinib in stock?

Elsubrutinib is currently made to order / not held in immediate stock. Contact us for lead time.

Elsubrutinib

Product Specifications

CAS Number

1643570-24-4

Synonyms

ABBV-105

Target

BTK

Applications

Protein Tyrosine Kinase

Molecular Formula

C17H19N3O2

Additionnal Information

Elsubrutinib (ABBV-105) is a covalent, irreversible, potent, and highly selective inhibitor of Bruton’s Tyrosine Kinase (BTK), with an IC50 of 0.18 μM for BTK catalytic domain. It specifically inhibits BTK dependent cellular functions, including both BCR and FcγR mediated signaling. It also exhibits significant efficacy in pre-clinical mechanistic models of antibody production, as well as in models of rheumatoid arthritis and lupus.