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Vevorisertib trihydrochloride

Product Specifications

CAS Number

1416775-08-0

Synonyms

ARQ 751 trihydrochloride

Target

Akt

Applications

PI3K/Akt/mTOR

Molecular Formula

C35H38N8O.3ClH

Additionnal Information

Vevorisertib trihydrochloride (ARQ 751 trihydrochloride) is a selective, allosteric inhibitor of pan-AKT and AKT1-E17K mutant with Kd values of 1.2 nM and 8.6 nM, respectively. It also has IC50 values of 0.55, 0.81, and 1.3 nM for AKT1, AKT2, and AKT3, respectively and can be used for the research of cancer.

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