AMG-193
Product Specifications
CAS Number
2790567-82-5
Target
PRMT
Applications
Epigenetics
Molecular Formula
C22H19F3N4O3
Additionnal Information
AMG-193 is an orally active and MTA-cooperative inhibitor of PRMT5 with potent biochemical and cellular activity. AMG-193, in combination with MTA, selectively targets and inhibits the growth of MTAP-deficient tumor cells by suppressing PRMT5, with an IC50 of 0.107 μM, while sparing normal cells that possess wild-type MTAP. AMG-193 also exhibits antitumor activity.
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-5432R-BF555 100 µL
Phospho-MEK5 (Ser137) Polyclonal Antibody, AbBy Fluor™ 555 Conjugated
Sign In for Pricing
View Details