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Edralbrutinib

Product Specifications

CAS Number

1858206-58-2

Synonyms

TG-1701

Target

BTK

Applications

Protein Tyrosine Kinase

Molecular Formula

C26H21F2N5O3

Additionnal Information

Edralbrutinib (TG-1701) is an irreversible, highly specific, and potent inhibitor of Bruton's tyrosine kinase (BTK) . TG-1701 shows similar efficacy but greater selectivity compared to the first-in-class BTK inhibitor ibrutinib, with a Kd value of 3 nmol/L, in both in vitro and in vivo models of B-cell non-Hodgkin lymphoma (B-NHL) .

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