(R) -HTS-3 (GLXC-25878)
Product Specifications
CAS Number
2771208-83-2
Synonyms
GLXC-25878
Target
Others
Applications
Others
Molecular Formula
C17H18F2N2O
Additionnal Information
(R) -HTS-3 (GLXC-25878) is a potent, selective, and cell-active inhibitor of lysophosphatidylcholine acyltransferase 3 (LPCAT3) with an IC50 of 0.09 μM, an enzyme critical for synthesizing C20:4-containing phospholipids. It reduces arachidonic acid-d8 incorporation into phospholipids and mitigates RSL3-induced ferroptosis in HT-1080 and 786-O cancer cells.
Storage Conditions
2 years -20°C liquid
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