M3541
Product Specifications
CAS Number
1360628-91-6
Target
ATM/ATR
Applications
PI3K/Akt/mTOR
Molecular Formula
C23H17FN6O2
Additionnal Information
M3541 is a potent and selective inhibitor of ATM kinase activity with an IC50 value of 0.25 nM in cell-free assays. M3541 suppresses double-strand breaks (DSB) repair, clonogenic cancer cell growth and potentiates antitumor activity of ionizing radiation in cancer cell lines.
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