What is the catalog number for Brigimadlin?

The catalog number for Brigimadlin is C01703-5mg.

What sizes are available for Brigimadlin?

Brigimadlin is available in the following size(s): 5 mg.

Is Brigimadlin in stock?

Brigimadlin is currently made to order / not held in immediate stock. Contact us for lead time.

Brigimadlin

Product Specifications

CAS Number

2095116-40-6

Synonyms

BI 907828

Target

MDM2/MDMX

Applications

Apoptosis

Molecular Formula

C31H25Cl2FN4O3

Additionnal Information

Brigimadlin (BI 907828) is a potent, orally active inhibitor of E3 ubiquitin-protein ligase MDM-2. Brigimadlin inhibits MDM-2's suppression of the tumor suppressor p53. It promotes apoptosis and enhances the transcription of p53 targets such as p21 and PUMA in BT48, BT67, and BT73 cells.