I-138
Product Specifications
CAS Number
2098211-50-6
Target
DUB
Applications
Ubiquitin
Molecular Formula
C26H23F3N6O
Additionnal Information
I-138 is an orally active, potent reversible inhibitor of USP1-UAF1 with IC50 0f 4.1 nM. I-138 is structurally related to ML323 and induces the monoubiquitination of FANCD2 and PCNA in MDA-MB-436 cells and increases PCNA and FANCD2 monoubiquitination in HAP-1 USP1 WT cells.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1234614-01 0.02 mg (E-Coli)
Recombinant Erwinia carotovora Protein RecA (recA)
Sign In for Pricing
View Details MBS1234614-02 0.02 mg (Yeast)
Recombinant Erwinia carotovora Protein RecA (recA)
Sign In for Pricing
View Details