P62-mediated mitophagy inducer
Product Specifications
CAS Number
1809031-84-2
Synonyms
PMI
Target
Mitophagy
Applications
Autophagy
Molecular Formula
C14H9IN4O2
Additionnal Information
P62-mediated mitophagy inducer (PMI) is a P62-mediated activator of mitophagy that functions independently of parkin recruitment or mitochondrial membrane potential (ΔΨm) collapse. It remains effective even in cells lacking a fully functional PINK1/Parkin pathway. PMI stabilizes Nrf2 and enhances p62 expression, thereby activating mitophagy.
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