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Tinengotinib

Product Specifications

CAS Number

2230490-29-4

Synonyms

TT-00420

Target

Aurora Kinase

Applications

Cell Cycle

Molecular Formula

C20H19ClN6O

Additionnal Information

Tinengotinib (TT-00420) is a novel multiple kinase inhibitor that strongly inhibits Aurora A/B with IC50 values of 1.2/3.3 nM respectively. It also exhibits potent inhibitory activity on FGFR1/2/3, VEGFR1, JAK1/2, and CSF1R and can be used to treat several prominent signaling pathways in triple-negative breast cancer (TNBC) .

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