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LY3537982 (KRAS G12C inhibitor 19)

Product Specifications

CAS Number

2649788-46-3

Target

Ras

Applications

Apoptosis

Molecular Formula

C25H19ClF2N4O3S

Additionnal Information

LY3537982 (KRAS G12C inhibitor 19) is a highly selective and potent inhibitor of the KRAS-G12C protein. LY3537982 selectively inhibits the growth of KRAS G12C mutant cells H23 G12C, H358 G12C, and H2122 G12C with IC50s of 1.04 nM, 1.16 nM, and 11.38 nM, respectively.

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