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Nesuparib

Product Specifications

CAS Number

2055357-64-5

Synonyms

JPI-547, NOV140201

Target

PARP

Applications

DNA Damage/DNA Repair

Molecular Formula

C23H24N6O

Additionnal Information

Nesuparib (JPI-547, NOV140201) is a potential inhibitor of both PARP and tankyrases, with IC50 of 0.005 μM, 0.001 μM, 0.002 μM, and ND for TNKS1, TNKS2, PARP1, and PARP2, respectively. Nesuparib exhibits anti-tumor activity in BRCA-deficient xenograft models.

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