JKE-1674
Product Specifications
CAS Number
2421119-60-8
Target
Peroxidases
Applications
Metabolism
Molecular Formula
C20H20Cl2N4O4
Additionnal Information
JKE-1674 is an analog of ML-210 in which the nitroisoxazole ring is replaced with an α-nitroketoxime. It is an orally active inhibitor of glutathione peroxidase 4 (GPX4) and also is an active metabolite of GPX4 inhibitor ML-210. JKE-1674 can convert into a nitrile oxide JKE-1777.
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