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SRI-37330 HCl

Product Specifications

CAS Number

2322245-49-6

Synonyms

EX-A5854

Target

Others

Applications

Others

Molecular Formula

C16H19F3N4O2S.ClH

Additionnal Information

SRI-37330 HCl (EX-A5854), an anti-diabetic drug, is an orally bioavailable inhibitor of thioredoxin-interacting protein (TXNIP), with an IC50 of 0.64 μM for TXNIP expression in INS-1 cells. Its treatment inhibits glucagon secretion and function, decreases hepatic glucose production, and reverses hepatic steatosis.

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