SRI-37330 HCl
Product Specifications
CAS Number
2322245-49-6
Synonyms
EX-A5854
Target
Others
Applications
Others
Molecular Formula
C16H19F3N4O2S.ClH
Additionnal Information
SRI-37330 HCl (EX-A5854), an anti-diabetic drug, is an orally bioavailable inhibitor of thioredoxin-interacting protein (TXNIP), with an IC50 of 0.64 μM for TXNIP expression in INS-1 cells. Its treatment inhibits glucagon secretion and function, decreases hepatic glucose production, and reverses hepatic steatosis.
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