Barbadin
Product Specifications
CAS Number
356568-70-2
Target
Apoptosis
Applications
0
Smiles
O=C1C (C (C2=CC=C (CC3=CC=CC=C3) C=C2) =CS4) =C4N=CN1N
Molecular Formula
C19H15N3OS
Additionnal Information
Barbadin is a selective β-arrestin/β2-adaptin interaction inhibitor with IC50 values of 19.1 μM (β-arrestin1) and 15.6 μM (β-arrestin2) . It inhibits agonist-induced endocytosis of β2-adrenergic, V2-vasopressin, and angiotensin-II type-1 receptors. Additionally, Barbadin exhibits pro-apoptotic activity.
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