CSN5i-3
Product Specifications
CAS Number
2375740-98-8
Smiles
O=C (C1=CC (C (F) F) =NN1C (C) C) NC2=CC (C3=CC=CC=C3) =C ([C@@H]4N5C (CCC[C@@H]4O) =CN=C5) C=C2
Molecular Formula
C28H29F2N5O2
Additionnal Information
CSN5i-3 is a selective, orally bioavailable CSN5/Jab1 inhibitor that demonstrates potent activity in suppressing CSN-mediated Cul1 deneddylation, exhibiting an IC50 of 5.8 nM.
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