Tenapanor
Product Specifications
CAS Number
1234423-95-0
Synonyms
AZD1722, RDX5791
Target
Sodium Channel
Applications
Transmembrane Transporters
Molecular Formula
C50H66Cl4N8O10S2
Additionnal Information
Tenapanor (AZD1722, RDX5791) is a potent and orally active inhibitor of sodium/hydrogen exchanger isoform 3 (NHE3) . It exhibits an IC50 of 2 and 6 nM in human and mouse ileum monolayers, respectively. Tenapanor reduces intestinal phosphate absorption predominantly by reducing passive paracellular phosphate flux.
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