MS177
Product Specifications
CAS Number
2225938-86-1
Target
Histone Methyltransferase
Applications
Epigenetics
Molecular Formula
C48H55N11O8
Additionnal Information
MS177 is an EZH2-targeting PRTOAC degrader and a potent inhibitor of enzymatic EZH2, that effectively depletes both canonical EZH2–PRC2 and noncanonical EZH2–cMyc complexes. MS177 induces leukemia cell growth inhibition, apoptosis, and cell cycle progression arrest.
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