Pan-RAS-IN-1
Product Specifications
CAS Number
1835283-94-7
Target
Ras
Applications
Apoptosis
Smiles
NC1 (CCNCC1) C (=O) NCCC[N]2C=C (C3=CC=C (OC (F) (F) F) C=C3) C4=C2C=CC (=C4) CN5CCN (CC5) CC6=C (Cl) C=CC=C6Cl
Molecular Formula
C36H41Cl2F3N6O2
Additionnal Information
Pan-RAS-IN-1, a pan-Ras inhibitor, binds to KRasG12D-GppNHp with a Kd less than 20 μM in MST, ITC and NMR assays, also binds to Ras proteins and exhibits lethality in cells partially dependent on expression of Ras proteins.
Storage Conditions
3 years -20°C powder
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