What is the catalog number for DS18561882?

The catalog number for DS18561882 is C18296-1mg.

What sizes are available for DS18561882?

DS18561882 is available in the following size(s): 1 mg.

Is DS18561882 in stock?

DS18561882 is currently made to order / not held in immediate stock. Contact us for lead time.

DS18561882

Product Specifications

CAS Number

2227149-22-4

Smiles

CS (=O) (NC1=CC=C (C (N2CCC (C3=CC=C (N4C[C@H] (C) N (C) CC4) C (C) =C3O5) =C (C5=O) C2) =O) C=C1OC (F) (F) F) =O

Molecular Formula

C28H31F3N4O6S

Additionnal Information

DS18561882 is a potent, isozyme-selective, and orally available inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) with an IC50 value of 0.0063 μM. It exhibits complete tumor growth inhibition in a mouse xenograft model, and shows potential as an anti-cancer agent.