SIRT7 inhibitor 97491
Product Specifications
CAS Number
1807758-81-1
Target
Sirtuin
Applications
DNA Damage/DNA Repair
Smiles
NC1=CC=CC (=C1) NC2=NC=C (O2) C3=CC=C (Cl) C=C3
Molecular Formula
C15H12ClN3O
Additionnal Information
SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC880040-500 1x 500 µL
CD35 / CR1 (E11), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400034-100 1x 100 µL
Cytokeratin 8/18 (C-51), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
