SKLB-197
Product Specifications
CAS Number
2713577-16-1
Target
ATM/ATR
Applications
PI3K/Akt/mTOR
Smiles
CC1COCCN1C2=NC (=NC3=C2C=C (C=C3) C4=CC=N[N]4C) C5=C6C=C[NH]C6=CC=C5
Molecular Formula
C25H24N6O
Additionnal Information
SKLB-197 exerts selectively inhibition against ataxia telangiectasia mutated and Rad3-related (ATR) kinase with IC50 of 0.013 μM, also displays potent antitumor activity against ATM-deficent tumors both in vitro and in vivo.
Storage Conditions
3 years -20°C powder
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