Ifebemtinib
Product Specifications
CAS Number
1227948-82-4
Synonyms
IN-10018, BI-853520
Target
FAK
Applications
Protein Tyrosine Kinase
Molecular Formula
C28H28F4N6O4
Additionnal Information
Ifebemtinib (IN10018, BI853520) is a highly selective, potent inhibitor of focal adhesion kinase (FAK), with an IC50 of 1 nM for inhibiting FAK autophosphorylation. It also inhibits FER Kinase and FES Kinase with IC50s of 900 nM and 1040 nM, respectively, inhibiting spheroid formation and orthotopic tumor growth in malignant pleural mesothelioma. IN10018 exhibits anti-tumor activity in vitro and in vivo.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
VAng-Yyj1770-50gEcoli 50 µg (E. coli)
Recombinant Mycobacterium Leprae pgk Protein (aa 1-416)
Sign In for Pricing
View Details 