GS-621763
Product Specifications
CAS Number
2647442-13-3
Target
SARS-CoV
Applications
Microbiology
Smiles
CC (C) C (=O) OCC1OC (C#N) (C (OC (=O) C (C) C) C1OC (=O) C (C) C) C2=CC=C3[N]2N=CN=C3N
Molecular Formula
C24H31N5O7
Additionnal Information
GS-621763, an orally bioavailable prodrug of GS-441524, shows a dose-dependent antiviral effect on SARS-CoV-2 reporter virus expressing nanoluciferase (SARS-CoV-2 nLUC) replication with an EC50 of 2.8 μM, also inhibits reporter SARS-CoV-2 expressing firefly luciferase (SARS-CoV-2 Fluc) replication with EC50 of 0.125 μM.
Storage Conditions
3 years -20°C powder
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