Voclosporin
Product Specifications
CAS Number
515814-01-4
Synonyms
ISA247, ISATX247
Target
Phosphatase
Applications
Metabolism
Molecular Formula
C63H111N11O12
Additionnal Information
Voclosporin is a potent, inhibitor of Calcineurin. It exhibits both immunomodulatory and non-immune effects by inhibiting T-cell proliferation, reducing proteinuria through podocyte cytoskeleton stabilization and afferent arteriole vasoconstriction, and effectively suppressing lymphocyte proliferation and cytokine production, making it useful for systemic lupus erythematosus (SLE) research.
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