Aficamten (CK-274)

2364554-48-1

CK 3773274

Cardiac Myosin

Cytoskeletal Signaling

CCC1=NC (=NO1) C2=CC=C3C (CCC3=C2) NC (=O) C4=C[N] (C) N=C4

C18H19N5O2

Aficamten (CK-274, CK 3773274) is a novel cardiac myosin inhibitor that reduces myocardial contractility in vitro and in vivo with an IC50 of 1.4 μM.

3 years -20°C powder