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Aficamten (CK-274)

Product Specifications

CAS Number

2364554-48-1

Synonyms

CK 3773274

Target

Cardiac Myosin

Applications

Cytoskeletal Signaling

Smiles

CCC1=NC (=NO1) C2=CC=C3C (CCC3=C2) NC (=O) C4=C[N] (C) N=C4

Molecular Formula

C18H19N5O2

Additionnal Information

Aficamten (CK-274, CK 3773274) is a novel cardiac myosin inhibitor that reduces myocardial contractility in vitro and in vivo with an IC50 of 1.4 μM.

Storage Conditions

3 years -20°C powder

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