What is the catalog number for GW280264X?

The catalog number for GW280264X is C01426-1mg.

What sizes are available for GW280264X?

GW280264X is available in the following size(s): 1 mg.

Is GW280264X in stock?

GW280264X is currently made to order / not held in immediate stock. Contact us for lead time.

GW280264X

Product Specifications

CAS Number

866924-39-2

Molecular Formula

C28H41N5O6S

Additionnal Information

GW280264X is a potent hydroxamate inhibitor of mixed ADAM10/TACE (ADAM17) . It potently blocks TACE (ADAM17) and ADAM10 with IC50s of 8.0 nM and 11.5 nM, respectively. It inhibits constitutive and PMA-inducible CX3CL1 shedding and increases adhesive properties in CX3CL1 transfected cells. Its treatment significantly improves functional recovery after spinal cord injury.