BRD0639
Product Specifications
CAS Number
2760881-74-9
Target
PRMT
Applications
Epigenetics
Smiles
CC (N1N=CC (=CC1=O) Cl) C (=O) NC2=CC=C (C) C (=C2) [S] (=O) (=O) NCCC3=NC=CC=C3
Molecular Formula
C21H22ClN5O4S
Additionnal Information
BRD0639 is a first-in-class PBM-competitive small molecule inhibitor that disrupts the PRMT5-RIOK1 complex with IC50s of 7.5 μM and 16 μM in permeabilized and living cells, respectively.
Storage Conditions
3 years -20°C powder
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