Aminopterin
Product Specifications
CAS Number
54-62-6
Synonyms
4-amino Folic Acid, 4-amino PGA, 4-Aminofolic acid, 4-Aminopteroylglutamic acid, Aminopteroylglutamic acid, APGA, NSC 739
Target
DHFR
Applications
Cell Cycle
Smiles
NC1=NC (=C2N=C (CNC3=CC=C (C=C3) C (=O) NC (CCC (O) =O) C (O) =O) C=NC2=N1) N
Molecular Formula
C19H20N8O5
Additionnal Information
Aminopterin (4-amino Folic Acid, 4-amino PGA, 4-Aminofolic acid, 4-Aminopteroylglutamic acid, Aminopteroylglutamic acid, APGA, NSC 739), a folic acid antagonist, is a competitive inhibitor of dihydrofolate reductase (DHFR) with Ki of 3.7 pM.
Storage Conditions
3 years -20°C powder
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