COH-SR4
Product Specifications
CAS Number
73439-19-7
Target
AMPK
Applications
PI3K/Akt/mTOR
Smiles
ClC1=CC (=CC (=C1) NC (=O) NC2=CC (=CC (=C2) Cl) Cl) Cl
Molecular Formula
C13H8Cl4N2O
Additionnal Information
COH-SR4 suppresses adipogenesis in 3T3-L1 cells through indirect activation of AMPK and downstream modulation of the Mammalian target of rapamycin complex 1 (mTORC1) signaling pathway, which blocks important regulators involved in protein synthesis, cell cycle progression, and expression of key transcription factors and their target adipogenic genes involved in lipid synthesis.
Storage Conditions
3 years -20°C powder
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