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ALLO-2

Product Specifications

CAS Number

1357350-60-7

Target

Hedgehog/Smoothened

Applications

Stem Cells & Wnt

Smiles

FC (F) (F) OC1=CC=C (C=C1) C2=NC (=NC=C2) NC3=CC4=C ([NH]N=C4) C=C3

Molecular Formula

C18H12F3N5O

Additionnal Information

ALLO-2 is a potent antagonist of both wild-type mouse Smo and drug-resistant D473H mutant human Smo that inhibits Smo agonist inhibited Gli-Luc activity in TM3-Gli-Luc cells with IC50 of 6 nM.

Storage Conditions

3 years -20°C powder

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