Sappanone A
Product Specifications
CAS Number
102067-84-5
Target
P38 MAPK
Applications
MAPK
Smiles
OC1=CC=C2C (=O) C (/COC2=C1) =C/C3=CC=C (O) C (=C3) O
Molecular Formula
C16H12O5
Additionnal Information
Sappanone A, a homoisoflavanone isolated from the heartwood of Caesalpinia sappan (Leguminosae), induces HO-1 expression by activating Nrf2 through the p38 MAPK pathway, suppresses LPS-induced NF-κB activation by suppressing the phosphorylation of RelA/p65 at Ser536, exerting its anti-inflammatory effect.
Storage Conditions
3 years -20°C powder
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