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Sappanone A

Product Specifications

CAS Number

102067-84-5

Target

P38 MAPK

Applications

MAPK

Smiles

OC1=CC=C2C (=O) C (/COC2=C1) =C/C3=CC=C (O) C (=C3) O

Molecular Formula

C16H12O5

Additionnal Information

Sappanone A, a homoisoflavanone isolated from the heartwood of Caesalpinia sappan (Leguminosae), induces HO-1 expression by activating Nrf2 through the p38 MAPK pathway, suppresses LPS-induced NF-κB activation by suppressing the phosphorylation of RelA/p65 at Ser536, exerting its anti-inflammatory effect.

Storage Conditions

3 years -20°C powder

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