What is the catalog number for Senicapoc (ICA-17043)?

The catalog number for Senicapoc (ICA-17043) is C01279-5mg.

What sizes are available for Senicapoc (ICA-17043)?

Senicapoc (ICA-17043) is available in the following size(s): 5 mg.

Is Senicapoc (ICA-17043) in stock?

Senicapoc (ICA-17043) is currently made to order / not held in immediate stock. Contact us for lead time.

Senicapoc (ICA-17043)

Product Specifications

CAS Number

289656-45-7

Target

Potassium Channel

Applications

Transmembrane Transporters

Smiles

NC (=O) C (C1=CC=CC=C1) (C2=CC=C (F) C=C2) C3=CC=C (F) C=C3

Molecular Formula

C20H15F2NO

Additionnal Information

Senicapoc (ICA-17043) is a Gardos channel (Ca2+-activated K+ channel; KCa3.1) blocker with an IC50 of 11 nM and produces dose-dependent increases in hemoglobin and decreases in markers of hemolysis. Senicapoc blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM.