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Calmidazolium chloride

Product Specifications

CAS Number

57265-65-3

Synonyms

R 24571

Target

PDE

Applications

Metabolism

Smiles

[Cl-].ClC1=CC=C (C=C1) C ([N]2C=C[N+] (=C2) CC (OCC3=CC=C (Cl) C=C3Cl) C4=C (Cl) C=C (Cl) C=C4) C5=CC=C (Cl) C=C5

Molecular Formula

C31H23Cl6N2O.Cl

Additionnal Information

Calmidazolium chloride (R 24571) is a calmodulin (CaM) antagonist, antagonizing CaM-stimulated fraction of rat brain phosphodiesterase and CaM-induced activation of erythrocyte Ca2+-transporting ATPase with IC50s of 0.15 and 0.35 μM, respectively, also shows a CaM-binding Kd value of 3 nM.

Storage Conditions

3 years -20°C powder

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