7BIO
Product Specifications
CAS Number
916440-85-2
Synonyms
7-bromoindirubin-3-oxime
Target
CDK
Applications
Cell Cycle
Smiles
O\N=C1\C (NC2=CC=CC=C12) =C/3C (=O) NC4=C (Br) C=CC=C34
Molecular Formula
C16H10BrN3O2
Additionnal Information
7-bromoindirubin-3-oxime (7BIO), an indirubin derivative derived from indirubin-3-oxime, possesses inhibitory effects against cyclin-dependent kinase-5 (CDK5) and glycogen synthase kinase-3β (GSK3β), also potently inhibits Aβ oligomer-induced neuroinflammation, synaptic impairments, tau hyper-phosphorylation, and activation of astrocytes and microglia.
Storage Conditions
3 years -20°C powder
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