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BMS-986122

Product Specifications

CAS Number

313669-88-4

Target

Opioid Receptor

Applications

Neuronal Signaling

Smiles

COC1=CC=C (C=C1Br) C2SCCN2[S] (=O) (=O) C3=CC=C (Cl) C=C3

Molecular Formula

C16H15BrClNO3S2

Additionnal Information

BMS-986122 is a selective, potent positive allosteric modulator of the mu-opioid receptor (μ-OR), shows potentiation of orthosteric agonist-mediated β-arrestin recruitment, adenylyl cyclase inhibition, and G protein activation, and potentiates DAMGO-mediated [35S]GTPγS binding in mouse brain membranes.

Storage Conditions

3 years -20°C powder

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