LDC195943 (IMT1)
Product Specifications
CAS Number
2304621-31-4
Synonyms
IMT1
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Molecular Formula
C21H21NO4
Additionnal Information
LDC195943 (IMT1) is a specific and noncompetitive inhibitor of human mitochondrial RNA polymerase (POLRMT) . IMT1 causes a conformational change of POLRMT, which blocks substrate binding and transcription in a dose-dependent way in vitro. IMT1 reduces deoxynucleoside triphosphate levels and citric acid cycle intermediates, resulting in a marked depletion of cellular amino acid levels. IMT1 has the potential for mitochondrial transcription disorders related diseases.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![GAPDH (Loading Control) Mouse Monoclonal Antibody [Clone ID: AT8G4]](https://cdn.genprice.uk/products/937/68dd189b061270361e8fc511/imageurl/am09367pu-s.webp)
AM09367PU-S 50 µL
GAPDH (Loading Control) Mouse Monoclonal Antibody [Clone ID: AT8G4]
Sign In for Pricing
View Details 
PKSH030343 50 µg
Recombinant Human DAPK1/DAP Kinase 1 Protein (aa 1-363, His & GST Tag)
Sign In for Pricing
View Details