AS1949490
Product Specifications
CAS Number
1203680-76-5
Target
SHIP
Applications
Metabolism
Smiles
CC (NC (=O) C1=C (OCC2=CC=C (Cl) C=C2) C=CS1) C3=CC=CC=C3
Molecular Formula
C20H18ClNO2S
Additionnal Information
AS1949490, a competitive inhibitor of 5'-lipid phosphatase SHIP2 with IC50 values of 0.62 μM and 0.34 μM for human (Ki value is 0.44 μM) and mouse respectively, promotes protein kinase C-dependent stabilization of brain-derived neurotrophic factor mRNA in cultured cortical neurons.
Storage Conditions
3 years -20°C powder
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