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SGC-AAK1-1

Product Specifications

CAS Number

2247894-32-0

Smiles

O=C (C1CC1) NC2=NNC3=C2C=CC (C4=CC=CC (NS (=O) (N (CC) CC) =O) =C4) =C3

Molecular Formula

C21H25N5O3S

Additionnal Information

SGC-AAK1-1 is a chemical probe that functions as a potent and selective inhibitor of AAK1 (AP2-associated kinase 1), exhibiting an IC50 of 270 nM and a Ki of 9 nM. It also demonstrates strong inhibitory activity against BMP2K. This compound serves as a research tool for investigating the Wnt pathway associated with AAK1.

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