Pseudolaric Acid A
Product Specifications
CAS Number
82508-32-5
Target
HSP (HSP90)
Applications
Cytoskeletal Signaling
Molecular Formula
C22H28O6
Additionnal Information
Pseudolaric acid A, a Hsp90 inhibitor with an IC50 of 0.60 μM, 2.72 μM, 1.36 μM, 2.92 μM and 6.16 μM in HL-60, A549, SMMC-7721, HeLa and SW480 cells respectively, is the main bioactive ingredient in Pseudolarix cortex, and induces cell cycle arrest at G2/M phase and promotes cell death through caspase-8/caspase-3 pathway, demonstrating potent antiproliferation and anticancer activities.
Storage Conditions
3 years -20°C powder
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