Chelerythrine
Product Specifications
CAS Number
34316-15-9
Synonyms
Toddaline, Broussonpapyrine
Target
PKC
Applications
Cytoskeletal Signaling
Smiles
COC1=C (OC) C2=C[N+] (=C3C (=C2C=C1) C=CC4=CC5=C (OCO5) C=C34) C
Molecular Formula
C21H18NO4
Additionnal Information
Chelerythrine (Toddaline, Broussonpapyrine) is a potent, selective antagonist of PKC with an IC50 of 0.66 μM. Chelerythrine also inhibits the BclXL-Bak BH3 peptide binding with an IC50 of 1.5 μM. Chelerythrine shows antitumor, antidiabetic and anti-inflammatory activity.
Storage Conditions
3 years -20°C powder
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