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2-BP (2-Bromohexadecanoic acid)

Product Specifications

CAS Number

18263-25-7

Synonyms

2-bromopalmitate

Target

Transferase

Applications

Metabolism

Smiles

CCCCCCCCCCCCCCC (Br) C (O) =O

Molecular Formula

C16H31BrO2

Additionnal Information

2-BP (2-Bromohexadecanoic acid) is a nonmetabolisable analogue of palmitate and acts as a palmitoylation inhibitor, which inhibits multiple palmitoyl-acyl transferase (PAT) activity towards MyrGCK (NBD) and FarnCNRas (NBD) with identical IC50s of approx. 4 μM. 2-Bromohexadecanoic acid can directly and irreversibly inhibit the palmitoyltransferase activity of all DHHC (Asp-His-His-Cys) proteins.

Storage Conditions

3 years -20°C powder

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