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Simufilam

Product Specifications

CAS Number

1224591-33-6

Synonyms

PTI-125

Target

Beta Amyloid

Applications

Neuronal Signaling

Smiles

CN1CCC2 (CC1) NCC (=O) N2CC3=CC=CC=C3

Molecular Formula

C15H21N3O

Additionnal Information

Simufilam (PTI-125) is a potent, orally active small drug against AD, which interacts to filamin and controls the actin cytoskeleton. Simufilam reduces tau hyperphosphorylation, amyloid and tau formation by preventing and reversing the binding of Aβ42 to α7 nAChR.

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