Simufilam
Product Specifications
CAS Number
1224591-33-6
Synonyms
PTI-125
Target
Beta Amyloid
Applications
Neuronal Signaling
Smiles
CN1CCC2 (CC1) NCC (=O) N2CC3=CC=CC=C3
Molecular Formula
C15H21N3O
Additionnal Information
Simufilam (PTI-125) is a potent, orally active small drug against AD, which interacts to filamin and controls the actin cytoskeleton. Simufilam reduces tau hyperphosphorylation, amyloid and tau formation by preventing and reversing the binding of Aβ42 to α7 nAChR.
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