Vodobatinib (K0706)
Product Specifications
CAS Number
1388803-90-4
Synonyms
SCO-088, SUN K706, SUN-K0706
Target
Bcr-Abl
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C=C (C=C1) C (=O) NNC (=O) C2=C (C) C=CC=C2Cl) C#CC3=CC4=CC=CC=C4N=C3
Molecular Formula
C27H20ClN3O2
Additionnal Information
Vodobatinib (K0706, SCO-088, SUN K706, SUN-K0706) is a novel BCR-ABL1 tyrosine kinase inhibitor with an IC50 of 7 nM. Vodobatinib exhibits activity against most BCR-ABL1 point mutants with IC50s of 167 nM, 154 nM,165 nM and 1967 nM for BCR-ABL1L248R, BCR-ABL1Y253H , BCR-ABL1E255V and BCR-ABL1T315I, respectively.
Storage Conditions
3 years -20°C powder
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