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A-779

Product Specifications

CAS Number

159432-28-7

Target

Angiotensin Receptor

Applications

GPCR & G Protein

Smiles

CCC (C) C (NC (=O) C (CC1=CC=C (O) C=C1) NC (=O) C (NC (=O) C (CCCNC (N) =N) NC (=O) C (N) CC (O) =O) C (C) C) C (=O) NC (CC2=CN=C[NH]2) C (=O) NC (C) C (O) =O

Molecular Formula

C39H60N12O11

Additionnal Information

A-779 is a potent and selective antagonist for Angiotensin- (1-7) (Ang- (1-7) ) with an IC50 of 0.3 nM in a radioligand binding assay. A-779 shows no significant affinity for AT1 or AT2 receptors at a concentration of 1 μM.

Storage Conditions

3 years -20°C powder

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